Design
- Placebo-controlled & double-blind
- 3 treatment arms: Placebo vs 6 or 12 weeks cytisinicline
Cytisinicline treatment for 6 or 12 weeks
- Does longer treatment lead to better efficacy?
- Does continued treatment prevent early relapses?
- Primary Endpoint: 4-week continuous abstinence ON treatment
- Follow up to 6 months
ORCA-2 Trial Locations
ORCA-2 is being conducted at the following locations in the US.
Atlanta Clinical Research
The General Hospital Coporation
d/b/a Massachusetts General Hospital
FutureSearch Trials of Dallas
MediSphere Medical Research Center, LLC
Alliance for Multispecialty Research (CPR)
Alliance for Multispecialty Research
(Volunteer Research Group)
Alliance for Multispecialty Research
(AMR Las Vegas)
(AMR Las Vegas)
Alliance for Multispecialty Research
(Central Kentucky Research)
(Central Kentucky Research)
Alliance for Multispecialty Research
(Clinical Research of South Florida)
(Clinical Research of South Florida)
Alliance for Multispecialty Research
(Coastal Clinical Research)
(Coastal Clinical Research)
Coastal Carolina Research
Alliance for Multispecialty Research
(New Orleans Center for Clinical Research)
Alliance for Multispecialty Research
(Tidewater Clinical Research Associates)
Arizona State University
M3 Wake Research, Inc.
Rochester Clinical Research
Alliance for Multispecialty Research
(Heartland Research)